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Revolutionizing Skincare: Harnessing the Potential of Regenerative Ingredients

By The Aesthetic GUIDE posted Aug 10, 2023 06:38 PM

  

In 2022, the global beauty market – defined as skincare, fragrances, makeup and haircare – generated around $430 billion in revenue, according to McKinsey & Company. By 2027, the overall beauty market is expected to reach $580 billion, with the fastest growth occurring in the premium skincare market.

Used as stand-alone therapy, and incorporated before, during and after device-based treatments, the well-established synergistic relationship between topical skincare and cosmetic procedures continue to evolve and expand. One of the most talked-about new entrants to the U.S. market – exosome-based topicals – join an array of newer preparations featuring growth factors, stem cells and even polydioxanone (PDO).

“As new product categories such as regenerative medicine-based approaches are introduced into topical skincare, it is important to recognize their independent mode of action,” explained Saranya Wyles, MD, PhD, dermatologist and assistant professor of dermatology and regenerative medicine at the Mayo Clinic* (Rochester, Minn.). “It could disrupt the dogma that a multi-step regimen is needed. Perhaps the same purposes can be achieved with fewer products, or one “holy grail” product,” she continued.

Exosomes & Growth Factors

Along with time-honored ingredients such as retinoids, Dr. Wyles said, newer regenerative products such as extracellular vesicles or regenerative nanotechnology, also called exosomes, may perform multiple skincare functions. However, she noted, product effects vary considerably based on their sources.

Popular exosome sources for cosmetics include platelets, mesenchymal stem cells and plant based. “Platelet-based technology contributes to ideal regeneration, as platelets play a key role in skin rejuvenation, wound healing and other mechanisms,” Dr. Wyles reported.

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Let us know in the comments which skincare treatment was your favorite from the feature!


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