Anti-aging hormone therapies allow patients to reclaim hope of counteracting age-related hormonal changes. With nearly 48% of menopausal American women taking hormone therapies, this industry is already a multi-billion-dollar business expected to reach around $53 billion by 2030. Francisco Llano, MD, a specialist in nutrition and anti-aging in Mexico City, Mexico, compares the endocrine system to an orchestra. “One out-of-tune hormone can result in significant changes to some of the body’s standard processes,” he said. In addition to skin aging, waning hormone levels manifest as weight gain, energy loss, decreased sex drive, sleepless nights, memory loss, mood swings, hot flashes, decreased muscle mass and more. As the sex hormones estrogen (estradiol), progesterone, and testosterone lessen, shifts in bone health, protein synthesis, and muscle mass transpire in both sexes. “There is this idea that only sex hormones age, but all hormones age,” Dr. Llano reported. Take, for example, declining ...